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One of the great ironies of depression treatment is that while depression can rob you of your desire for sex, the drugs that treat it can be much worse, causing not only low libido, but also erectile dysfunction and difficulties with orgasm. The following are some tips that you may wish to discuss with your doctor that can help restore you sex life.
Under the supervision of a physician, it may be possible to lower your dose enough to reduce sexual side effects while still obtaining depression relief. For example, it has been shown that for some people 5-10 mg of Prozac may be just as effective as the standard 20 mg dose.
With certain drugs, such as sertraline and clomipramine (brand names Zoloft and Anafranil), it may be possible to schedule your daily dose right after the time you would normally expect to engage in sexual activity, when the drug's level in your body would be at its lowest.
For example, if you normally have sex at night, schedule your daily dose near that time and take it just after sex.
Case repors and small clinical studies have found the following to be potentially helpful in counteracting sexual dysfunction: Amantadine, Bupropion, Buspirone, Cyproheptadine, Dextroamphetamine, Pemoline and Yohimbine. Your doctor may suggest taking the drug prior to sexual activity or may put you on a daily regimen.
Drugs targeted at erectile dysfunction, such as Viagra, may help some patients.
With the drugs sertraline and paroxetine (brand names Zoloft and Paxil) it may be possible to schedule a two day drug holiday each week in order to restore sexual function without losing the efficacy of the antidepressant.
Nefazodone and bupropion (brand names Serzone and Wellbutrin) have been shown in double-blind studies to have less effect on sexual function than SSRIs. If either of these have an adequate antidepressant effect for an individual patient they may be a viable treatment alternative to reduce sexual side effects.